Tadalafil

I-CMOAPI inoluhlu olupheleleyo lwezinto ezibunjiweyo zeTadalafil, kwaye inolawulo olupheleleyo lwenkqubo.Also yadlula i-GMP kunye nesiqinisekiso se-DMF.

Ebonisa zonke iziphumo 3

Yintoni iTadalafil

I-Tadalafil sisiyobisi esinyangiweyo esisetyenziselwa ukunyanga ukungasebenzi kakuhle kwe-erectile (ED) kunye neempawu ze-Prostate eyandisiweyo emadodeni. Kukwabonakalisiwe ukunyanga uxinzelelo lwegazi kwimiphunga (PAH).
I-Tadalafil (Inombolo ye-CAS: 171596-29-5) ifumaneka ngohlobo lwethebhulethi yomlomo okanye i-tadalafil powder kwaye ithengiswa ikakhulu phantsi kwegama leCialis (ye-erectile dysfunction okanye i-benign prostate enlargement) okanye i-Adcirca (ye-pulmonary arterial hypertension). I-Tadalafil ikwafumaneka ngohlobo lwayo oluqhelekileyo olungenakuba nawo onke amandla njengokwenza okokuqala


Isebenza njani i-tadalafil?

I-Tadalafil yenye ye-phosphodiesterase yohlobo lwe-5 (PDE5) inhibitors. Xa la maqela amachiza ethintela i-PDE5, nawo aya kuphucula ukusebenza kwe-erectile.
Ngexesha lokuvuselela inkanuko yesini, ulwakhiwo lwenzeka xa kukho ukuhamba kwegazi okwaneleyo kwimithambo ye-penile ekhokelela kwimithambo ekhululekile kunye nesihlunu esigudileyo se-corpus cavernosum. Le mpendulo imodareyithwa yimveliso ye-nitric oxide (NO) kwiiseli ze-endothelial kunye neeterminal terminals. Ukukhutshwa kwe-NO kukonyusa ukudityaniswa kwe-cyclic guanosine monophosphate (eyaziwa ngokuba yi-cyclic GMP okanye i-cGMP) kwiiseli zemisipha egudileyo. I-cyclic GMP inceda ukukhulula izihlunu ezigudileyo kunye nokunyusa ukuhamba kwegazi kwi-corpus cavernosum.
I-Tadalafil inqanda uhlobo lwe-phosphodiesterase yohlobo lwe-5 (PDE5) ngokwandisa inani le-cGMP. Kubalulekile ukuba uqaphele ukuba umntu kufuneka afumane ukuvuselelwa ngokwesini ukuze aqalise ukukhutshwa kwendalo kwe-nitric oxide. Kungenxa yokuba iimpembelelo zeTadalafil azizukwenzeka ngaphandle kokuvuselelwa ngokwesondo.
I-Tadalafil inokuzinciphisa iimpawu zedlala leprostate eyandisiweyo kubandakanya ukungxamiseka / ukuchama rhoqo, ubunzima bokuchama kunye nokungahambi kakuhle komchamo. Kufezekisa oku ngokuphumla kwezihlunu zeprotrate nakwisinyi.
Kwi-pulmonary hypertension, i-tadalafil inceda ukukhulula imithambo yegazi esifubeni. Oku kunceda ukwandisa ukubonelelwa kwegazi emiphungeni kwaye kunciphisa nomthwalo wentliziyo.


Abaphakathi beTadalafil

Kwinkqubo yokuvelisa i-tadalafil (i-CAS 151596-29-5), abanye abalamli bayenziwa. Ezinye iinkampani ziya kusebenzisa i-tadalafil intermediates ukuvelisa i-tadalafil.

I-171596-29-5

I-Tadalafil (i-CAS 171596-29-5) sisiyobisi esinamandla nesisebenzayo sokunyanga ukungasebenzi kakuhle kwe-erectile kunye nokwandiswa kwe-prostatic yokwanda emadodeni kunye ne-pulmonary arteries hypertension.

I-171489-59-1

ICas 171489-59-1 ikwabizwa ngokuba yiChloropretadalafil iphakathi kwimveliso yeTadalafil esetyenziselwa unyango lwe-erectile dysfunction. I-CAS 171489-59-1 inefomula yemolekyuli C22H19ClN2O5 enobunzima beemolekyuli ze-426.85 g / mol. Ifumaneka ngohlobo lokuqina okumhlophe.

I-171752-68-4

I-CAS 171752-68-4 eneemolekyuli zefomula eyi-C20H18N2O4.HCl kunye nobunzima beemolekyuli ze-386.83 g / mol nayo iphakathi tadalafil.
Baninzi abathengisi beetadalafil eziphakathi ezinikezela ngeetadalafil eziphakathi ezithengiswayo ngamaxabiso aphantsi. Nangona kunjalo, xa ucinga i-tadalafil yithenge kwiinkampani ezithembakeleyo ukuqinisekisa ukuba umgangatho awubandakanyi.
I-CMOAPI ngomnye wabathengisi abaphakathi be-tadalafil abaqinisekisa umgangatho ophakamileyo kunye namaxabiso okhuphiswano kwiimveliso zabo.


Ngubani kunye nendlela yokusebenzisa i-tadalafil

I-Tadalafil powder inganyanga oku kulandelayo emadodeni?

Ukungasebenzi kwe-Erectile

Ukungasebenzi kakuhle kwe-Erectile (i-ED) ekwabizwa ngokuba kukungabi namandla kuyimeko yamadoda apho angakwaziyo ukufumana okanye ukugcina ulwakhiwo ixesha elaneleyo lokuzibandakanya kwimicimbi yesondo. Ihlala ikhokelela kumdla kwezesondo kwaye inokubangela nezinye iingxaki ezinje ngaphambi kwexesha okanye ukulibaziseka ukunyuka kwaye ngamanye amaxesha ukungakwazi ukufikelela kwi-orgasm.
I-ED inokubangelwa zizizathu ezininzi zombini imeko yomzimba kunye neemvakalelo ezinje ngezifo ezithile ezinje ngesifo seswekile, isifo sentliziyo, kunye noxinzelelo lwegazi, ubudala, uxinzelelo, okanye ulwalamano.
I-Tadalafil inceda ukunyanga i-ED ngokwandisa ukuhamba kwegazi ukuya kwilungu lobudoda. Oku kunceda ukufezekisa kunye nokugcina ulwakhiwo. Nangona kunjalo, i-tadalafil inceda kuphela kulwakhiwo xa umntu sele evuselelekile ngokwesondo.

I-Benign prostatic hyperplasia (BPH)

Ikwabizwa ngokuba kukwandiswa kwe-prostate gland, i-BPH yimeko eqhelekileyo ehlala ifunyanwa emadodeni ebudaleni babo. Nangona kunjalo, ezinye izinto zinokukhokelela ekwandisweni kweprotate kubandakanya isifo seswekile kunye nokuphazamiseka kwentliziyo, indlela yokuphila, ngakumbi ukutyeba kunye nembali yosapho ye-BPH. Xa iprotrate ikhula inokubangela iimeko zokuchama.
Iimpawu ezinxulunyaniswa ne-Prostate gland eyandisiweyo yile, engxamisekileyo kunye nokuhlala urhalela ukukhupha umchamo, ukuba nzima ukuqala ukuchama, umjelo womchamo obuthathaka, okanye ukungakwazi ukukhupha isinyi ngokupheleleyo. Eminye imiqondiso ye-BPH inokubandakanya usulelo lwe-urinary tract (UTI), ukungakwazi ukuchama, okanye igazi kumchamo.
I-Tadalafil powder okanye ithebhulethi inceda ukuphumla imisipha kwiprostate nakwisinyi. Oku kunceda ukukhulula iimpawu ze-BPH.

I-pulmonary arteries hypertension (PAH)

I-PAH yimeko apho kukho uxinzelelo lwegazi oluphezulu kwimithambo ehambisa igazi kwimiphunga. Yahlukile kuxinzelelo lwegazi oluqhelekileyo. Kwenzeka xa imithambo yegazi esuka entliziyweni iye emiphungeni iba mxinwa okanye ivalekile.
Ezona mpawu zibalulekileyo zibandakanya iintlungu esifubeni, ukudinwa, okanye nokudumba emilenzeni nasezilindini.
I-Tadalafil inokunceda ekunciphiseni iimpawu ze-PAH ngokuphumla kwimithambo yegazi emiphungeni eyonyusa ngokulandelelana ukuhamba kwegazi.

Ungayisebenzisa njani i-tadalafil?

Idosi ye-tadalafil ixhomekeke kubudala bakho, ukusetyenziswa okucetywayo, kunye nayo nayiphi na eminye imiba yezonyango.
Ukusetyenziswa kweTadalafil akukhuthazwa kubantwana abangaphantsi kweminyaka yobudala be-18 ngelixa abaneminyaka engaphaya kwe-65 kufanelekile ukuba balumke kuba imizimba yabo ithatha ixesha elide ukufumana la machiza.
Kukho izikhokelo ezicacileyo zendlela yokusebenzisa i-tadalafil powder kodwa eyona fomu ixhaphakileyo yithebhulethi ye-tadalafil phantsi kwamagama eempawu ezahlukeneyo.
Kuyacetyiswa ukuba uthathe i-tadalafil kube kanye yonke imihla kwaye uyithathe malunga nexesha elifanayo yonke imihla ukufumana izibonelelo ze-tadalafil.
Idosi ye-tadalafil yokusetyenziswa ngeendlela ezahlukeneyo ichaziwe;
Ukungasebenzi kakuhle kwe-erectile, idosi ye-2.5-5 mg ithathwa yonke imihla okanye i-10 mg xa ithathwa kube kanye ngokwesidingo ngasinye.
Kwi-benign prostatic hyperplasia, idosi ye-5 mg ethathwa yonke imihla iyacetyiswa. I-Tadalafil kufuneka ithathwe kanye yonke imihla.
Xa ujongene neemeko zombini (ukungasebenzi kakuhle kwe-erectile kunye nokwandiswa kweprostate) idosi ye-5 mg ngosuku kufanelekile.
Ngxinzelelo lwegazi lwe-pulmonary arterial, idosi ye-tadalafil ye-40 mg ethathwa yonke imihla iyacetyiswa.
Njengazo zonke iziyobisi, into esebenzayo komnye ayinakwenza okufanayo komnye. Ezinye iindlela zeTadalafil zikhona. Nangona kunjalo, eyona nto intle ukuyenza kukuthetha nogqirha wakho malunga nezinye iindlela ezikhoyo ze-tadalafil kwaye ubone ukuba zeziphi ezifanelekileyo. Unokucetyiswa ukuba uthathe ezinye i-tadalafil ukuba uxabisa i-tadalafil okanye ngenxa yezinye izizathu.
Luxanduva lwakho ukuqaphela ukuba yintoni esebenzayo kakuhle kuwe ngelixa ulawula ukuba i-tadalafil lukhetho okanye iziphumo zecala ze-tadalafil zisuse izibonelelo ze-tadalafil.


Yintoni umahluko phakathi kweTadalafil kunye namanye amayeza okungasebenzi kakuhle kwe-erectile

ICialis (iTadalafil)

I-Cialis lunyango lonyango kwiklasi yeziyobisi ebizwa ngokuba yiPhosphodiesterase-5 Enzyme Inhibitors. Isetyenziselwa ukunyanga iimpawu zokungasebenzi kakuhle emzimbeni. Ingasetyenziselwa yodwa okanye iqokelelwe kunye nezinye iziyobisi.

I-Dapoxetine Hydrochloride

I-Dapoxetine hydrochloride ihlelwa njenge-serotonin reuptake inhibitors (SSRIs) ekhawulezayo.
I-Dapoxetine hydrochloride sisiyobisi esibhalisiweyo esisetyenziselwa ukunyanga ukuphuma kwangaphambi kwexesha. Ukuphuma ngaphambi kwexesha yimeko exhaphakileyo emadodeni ebandakanya ukungakwazi ukulibazisa ukunyuka. Olu luphawu olunye lokungasebenzi kakuhle kwamadoda.
Nangona zombini i-tadalafil kunye ne-dapoxetine hydrochloride zisetyenziselwa ukunyanga iimpawu ze-erectile dysfunction, enye i-tadalafil yi-phosphodiesterase inhibitor ngelixa enye, i-dapoxetine, ikhetha i-serotonin reuptake inhibitor.

IVardenafil Hydrochloride

IVardenafil liyeza kwiqela lamachiza abizwa ngokuba yi-phosphodiesterase (PDE) inhibitors. Isetyenziselwa ukunyanga ukungasebenzi kakuhle kwamadoda. Xa indoda ivuswa ngokwesondo, i-vardenafil yonyusa ukuhamba kwegazi ukuya kwilungu lobudoda eliqinisekisa ukuba ufumana ulwakhiwo.
IVardenafil ethengiswe phantsi kwegama lophawu lweLevitra lukhetha kakhulu kune-sildenafil kunye ne-tadalafil (Cialis) kwi-PDE5. Oku kuthetha ukuba idosi esezantsi ye-vardenafil iyafuneka ngeziphumo ebezingalindelekanga ezimbalwa ezinokubakho.
Omnye umahluko obonakalayo kwisiqingatha sobomi apho i-vardenafil (i-Levitra) ine-half-life ye-4-6 iiyure ngelixa i-tadalafil (Cialis) ine-half-life ye-17.5 iiyure. Oku kuthetha ukuba iTadalafil (Cialis) isebenza ixesha elide kune-vardenafil.

Avanafil

I-Avanafil sisiyobisi kwiqela le-phosphodiesterase inhibitors. Isetyenziselwa ukunyanga ukungasebenzi kakuhle kwe-erectile ngokuphucula ukuhamba kwegazi kwingingqi ye-penile.
Nangona zombini i-avanafil kunye ne-tadalafil ziyi-phosphodiesterase inhibitors, i-avanafil yeyona intsha kwaye inesiqingatha sobomi obufutshane malunga neeyure ezi-5 kune-tadalafil enobomi obunesiqingatha seyure eziyi-17.5.
Ukuqukumbela, i-tadalafil ilunge ngakumbi ngenxa yobomi bayo obude. Umntu unokuthatha iyeza ngokwenza iziphumo ebezingalindelekanga ezimbalwa ezinokwenzeka.


Iziphumo zecala leTadalafil kunye nezibonelelo

Izibonelelo zeTadalafil

Uninzi olujonga ukusebenzisa i-tadalafil powder ukuyithenga ngenxa yezona zibonelelo zayo eziphambili ze-tadalafil;

Ukunyanga ukungasebenzi kakuhle kwe-erectile

Ukwakhiwa kwePenile yinkqubo yokudibanisa imisebenzi yesondo. Ukungasebenzi kakuhle kwe-erectile kwenzeka xa indoda ingakwazi ukufumana kunye nokugcina ulwakhiwo. Oku kubangela imiba emininzi enje ngoxinzelelo, ukuzithemba okuphantsi, kunye neengxaki zobudlelwane.
Ukulungiswa kufezekiswa xa kukho ukuhamba kwegazi okwaneleyo kwilungu lobudoda. I-Tadalafil inceda ukukhulula iimpawu zokungasebenzi kakuhle ngokwandisa ukuhamba kwegazi ukuya kwilungu lobudoda.

Ukunyanga iimpawu ze-benign prostatic hyperplasia

I-Benign prostatic hyperplasia ikwabizwa ngokuba yi-prostate gland eyandisiweyo. Le yimeko eyenzeka ngokwendalo kunye nobudala. Xa i-prostate gland iyanda, iyancwina i-urethra. Ezinye zeempawu ezinxulunyaniswa neprostate eyandisiweyo zezi; Ukuchama okungxamisekileyo kunye nokuqhubekayo, kunzima ukuqala ukuchama, ukuchama kabuhlungu phakathi kwabanye.
I-Tadalafil iluncedo kumadoda aphethwe yi-benign prostatic hyperplasia ngokukhulula ezi mpawu. I-Tadalafil powder inceda ukuphumla i-prostate gland kunye ne-bladder ngaloo ndlela kunciphisa iimpawu ezihambelana ne-bladder kunye ne-urethra.

Unokunyanga kokubini ukungasebenzi kakuhle kwe-erectile kunye ne-benign prostatic hyperplasia

I-Tadalafil inokunceda amadoda aphethwe kukungasebenzi kakuhle kwe-erectile kunye nokwandiswa kwe-Prostate gland ngaxeshanye.
Xa usebenzisa i-tadalafil kumthamo olungileyo kwaye njengoko kucetyisiwe uvuna izibonelelo ezichaziweyo. Kuba ndonyusa ukuhamba kwegazi kwingingqi ye-penile nakwezinye iindawo, yindlela esempilweni yokujongana nezi meko.

Ingasetyenziselwa ukunyanga iimpawu zoxinzelelo lwegazi kwimiphunga

Uxinzelelo lwegazi lwe-pulmonary arterial (PAH) kuthetha ukuba kukho uxinzelelo lwegazi oluphezulu kwimithambo ethatha igazi lisuka entliziyweni liye emiphungeni. Kodwa yahlukile kuxinzelelo lwegazi oluqhelekileyo.
I-PAH yenzeka xa imithambo ebonelela ngegazi kwimiphunga iba mxinwa okanye ivalekile kukhokelela ekubeni intliziyo inyanzelwe ukuba ipompe igazi ngezinga eliphezulu. Oku kukhawuleza kunye nokunyanzelwa kwentliziyo kubangela uxinzelelo olukhulu kwimithambo.
I-Tadalafil powder iyamangalisa ngokuphumla kwemithambo yegazi. Oku kuphumla kuvumela ukuhamba kwegazi okuthe tye ngenxa yoko kunyusa izinga lokuhamba. Oku kunceda intliziyo ukuba impompe ukutyibilika kwegazi ngaloo ndlela isuse uxinzelelo oluya kuthi longezeleleke

Ukuphucula amandla akho omthambo

Ngexesha lokuhamba kwegazi kubalulekile ukuvumela umntu ukuba afumane i-oksijini eyaneleyo kunye nokuvelisa amandla aneleyo afunekayo.
I-Tadalafil inokunyusa ukusebenza kwakho ngokuzilolongela imithambo yegazi kunye nokunyusa ukuhamba kwegazi.

Iziphumo ebezingalindelekanga zeTadalafil

Iziphumo eziqhelekileyo ze-tadalafil zibandakanya;

  • Intloko ebuhlungu,
  • Isicaphucaphu,
  • ukucoca (ukufudumala, ubomvu, okanye ukuziva unomsindo),
  • isisu esiswini,
  • impumlo exineneyo okanye ebalekayo, kwaye
  • iintlungu zemisipha, iintlungu zomqolo, kunye neentlungu ezingalweni okanye emilenzeni.

I-Tadalafil inokukhokelela nakwimiphumo emibi kakhulu. Uyacetyiswa ukuba ufune uncedo lwezonyango ukuba ufumana naziphi na iziphumo ezilandelayo zetadalafil;

  • ezinye iimpawu zokuhlaselwa kwentliziyo kubandakanya iintlungu zesifuba, iintlungu zisasazeka emhlathini okanye egxalabeni, isicaphucaphu kunye nokubila.
  • utshintsho lombono kubandakanya ukungaboni kakuhle okanye ukulahleka kombono ngesiquphe.
  • ukucoca (ukufudumala, ubomvu, okanye ukuziva unomsindo),
  • Ukuva ukuphazamiseka kwi
  • ukukhala kwiindlebe zakho kunye nokulahleka kwendlebe
  • Ulwakhiwo olubuhlungu okanye oluhlala ixesha elide kuneeyure ezingama-4 njengoko oko kunokonakalisa ubudoda bakho.
  • Ukuvutha
  • Intliziyo engavumelekanga
  • Ukuphelelwa ngamandla, isiyezi kunye,
  • Ukudinwa okungaqhelekanga.

Ukusebenzisana kweziyobisi kweTadalafil

Unxibelelwano oluninzi lwe-tadalafil kunye nezinye iziyobisi zixeliwe. Ukudibana kweziyobisi kuhlala kuguqula umsebenzi wamayeza kwaye kunokubathintela ukuba basebenze ngokufanelekileyo.
Kucetyiswa kakhulu ukuba uxoxe ngamayeza akho ngaphambi kokuba usebenzise i-tadalafil. Olunye unxibelelwano lwe-tadalafil lunokuba nobulali kunye nolunye olubi.
Apha ngezantsi kukho unxibelelwano lwe-tadalafil;

Nitrates

Kukwabhekiswa kuzo njengeziyobisi zeAnguina. Xa i-nitrate ithathwa kunye ne-tadalafil, inokubangela ukuba uxinzelelo lwegazi luye kumanqanaba asezantsi kakhulu. Umgangatho ophantsi woxinzelelo lwegazi unxulunyaniswa neempawu ezinje ngesiyezi okanye nokudinwa.
Ezinye zezi ziyobisi zibuhlungu zibandakanya; I-butyl nitrite, i-amyl nitrite, isosorbide dinitrate, nitroglycerin, kunye ne-isosorbide mononitrate.

I-Alpha-blockers

La ngamachiza asetyenziselwa ukulungisa uxinzelelo lwegazi oluphezulu. Zikwasetyenziswa kunyango lweprostate. Zombini i-tadalafil kunye ne-alpha-blockers zii-vasodilator ezinefuthe lokunciphisa uxinzelelo lwegazi. Xa isetyenziswa kunye, inokubangela ukwehla okukhulu / okubalulekileyo kuxinzelelo lwegazi. Oku kubangela ukuba umntu abe nesiyezi kwaye angaphela amandla.
Ezinye zeziyobisi ze-alpha-blocker zibandakanya; terazosin, tamsulosin, alfuzosin, kunye neprazosin.

Ezinye iziyobisi ze-HIV

La machiza yi-protease inhibitors kwaye kungoko linokunyusa inqanaba le-tadalafil egazini. Olu konyuka lubangela uxinzelelo lwegazi olusezantsi. Inokubangela ukungakhathali emadodeni oko kuthetha ukuba bafumana ulwandiso olwandisiweyo oluhlala lubuhlungu.
Amanye ala machiza yi-ritonavir kunye ne-lopinavir.

Antibiotics

Ukudibana kweTadalafil kunye ne-antibiotics kuye kwaxelwa. Xa ithathiwe kunye ne-tadalafil, ii-antibiotics zinokunyusa inqanaba le-tadalafil egazini ekhokelela ekunciphiseni uxinzelelo lwegazi. Unokubangela isiyezi, ukuphelelwa ngamandla, kunye nemicimbi ethile yombono. Inokubangela nokukhathazeka emadodeni.
Amanye ala machiza yi-erythromycin, telithromycin, kunye ne-clarithromycin.
Nangona kunjalo, ii-antibiotics ezithile zingathoba amanqanaba e-tadalafil egazini. Olu nxibelelwano lwe-tadalafil alwenzi kakuhle. La machiza abandakanya; rifampin.

Iziyobisi ezichasayo

Ezinye iziyobisi ezichasayo zomlomo kubandakanya i-ketoconazole kunye ne-itraconazole inxibelelana ne-tadalafil.
Ezi ziyobisi zinokunyusa inqanaba le-tadalafil ekhokelela ekubeni nesiyezi kunye nokuphelelwa ngamandla kunokwenzeka.

Amanye amachiza oxinzelelo lwegazi kwimiphunga

I-Tadalafil kunye nezinye iziyobisi ze-pulmonary hypertension ziyaziwa ngokuba nefuthe lokunciphisa uxinzelelo lwegazi. Xa isetyenziswa kunye inokukhokelela kumanqanaba aphantsi oxinzelelo lwegazi. Oku kukhokelela kwiimpawu ezinxulumene noxinzelelo lwegazi ezinje ngesiyezi kunye nokuphelelwa ngamandla.
Amachiza abandakanya i-riociguat.

Iintsholongwane

La machiza asetyenziselwa ukunciphisa isisu esiswini. Xa zisetyenziswa ngokudibeneyo ne-tadalafil, zinokuthintela ukufunxwa kwe-tadalafil emzimbeni. Babandakanya i-magnesium hydroxide okanye i-aluminium hydroxide.

Amayeza okuxhuzula

Ezi zikwabizwa ngokuba ngamachiza okuthimba ukuhlutha. Xa uthatha iziyobisi ezichasene nokuthimba kunye ne-tadalafil, zinokuhlisa ukufunxwa kwe-tadalafil. Oku kuthetha ukuba i-tadalafil ayinakukwazi ukusebenza kakuhle. La machiza okuxhuzula aquka i-phenytoin, phenobarbital, kunye ne-carbamazepine.


Uyithenga phi iTadalafil?

Unokwenza iTadalafil ithenge kwiivenkile ezikwi-intanethi. Umgubo ufumaneka ngesixa esikhulu kubaphandi nakwabahlalutyi. Qiniseka ukuba ujonga i-tadalafil powder evunyiweyo yabanikezeli Xa ucinga ukuthatha i-tadalafil ithenge kubathengisi abathembekileyo.
Qhagamshelana nogqirha wakho ngaphambi kokuba uthathe i-tadalafil ngenxa yeempembelelo ze-tadalafil kunye nokusebenzisana kwe-tadalafil kunye nezinye iziyobisi.
Ukuba ujonga iTadalafil okanye abaphakathi, kuya kufuneka ungene kunye ne-CMOAPI ngonikezelo olusebenzayo lweemveliso ezisulungekileyo. Amakhompawundi ethu afumene isiqinisekiso somgangatho.


Tadalafil FAQ

Q: Ngaba i-tadalafil yomelele kune-Viagra?

A: I-Tadalafil (generic Cialis) inenzuzo ngaphezulu kweSildenafil kuba ihlala ixesha elide-ukuya kuthi ga kwiiyure ezingama-36 (xa kuthelekiswa neeyure ezingama-4-5 zeSildenafil). Amanye amadoda akhetha oku njengoko ivumela ukuzithemba okungaphezulu.

Umbuzo: Ngaba iCialis ikugcina unzima emva kokuza?

A: Sukuyithatha ukuba awuyidingi. Ingabangela umonakalo omkhulu.
Ngokwesiqhelo emva kokuza kusenobuntununtunu obungummangaliso emva kwe-orgasm, kwaye ihlala ingenakuchukunyiswa, kodwa emva kwemizuzu embalwa yokuyigcina ishushu ke inokuqhubeka.

Umbuzo: Ngaba i-20mg Cialis ininzi kakhulu?

A: Idosi ephezulu yeCialis enokuthi ithathwe ngemini yi-20 mg. Akufanele uthathe iCialis ngaphezu kweyodwa ngosuku. Kwezilingo zeklinikhi, uCialis wanceda abantu abaneempawu ze-ED ukuya kuthi ga kwiiyure ezingama-36 emva kwedosi yabo. Ke ukuba uthatha amayeza kuphela njengoko kufuneka, akufuneki ukuba uwathathe yonke imihla.

Umbuzo: Yintoni esebenza ngcono ngegragra okanye iCialis?

A: Umahluko omkhulu phakathi kweViagra kunye neCialis lixesha lempembelelo zabo. I-Viagra ihlala isebenza iiyure ezi-4 ukuya kwezi-6, ethi inike ithuba elaneleyo lokulala ngesondo amaxesha amaninzi ukuba unqwenela. Nangona kunjalo i-Cialis ikuvumela ukuba ufezekise ii-erections ukuya kuthi ga kwiiyure ezingama-36 emva kokuthatha ithebhulethi.

Umbuzo: Ihlala ixesha elingakanani indoda ephakathi iphakathi?

A: Ulwakhiwo lungahlala ukusuka kwimizuzu embalwa ukuya kwisiqingatha seyure. Ngokomndilili, amadoda anokulungiswa ezintlanu ebusuku ngelixa belele, nganye ihlala malunga nemizuzu engama-25 ukuya kwengama-35.

Q: Beminyaka mingaphi ukuba abafana banengxaki yokufumana ubunzima?

A: Malunga neepesenti ezi-5 zamadoda aneminyaka engama-40 ubudala ane-erectile dysfunction, kwaye elo nani lonyuka liye kufikelela kwiipesenti ezili-15 zamadoda aneminyaka engama-70. ipesenti yamadoda akuma-10s awo, ama-50 epesenti yamadoda akuma-50 awo).

Q: Kukangaphi indoda ifuna ukukhupha isidoda ngeveki?

A: nokuba uphilile kangakanani na, kwezonyango kufanelekile ukuba uvelise isidoda rhoqo kwiintsuku ezi-3 ukuya kwiveki enye ngeentsuku ezisi-1, ke ukubona ugqirha wakho kubaluleke kakhulu ukuyalela ngexesha ukuba kukho ukuphazamiseka.

Q: Kukuphi ukutya okukunceda ube nzima?

A: Ispinatshi ngowona mthombo ubalaseleyo we-folate, eyaziwayo yokuhamba kwegazi. I-acid ye-Folic idlala indima ebalulekileyo ekusebenzeni ngokwesini kwendoda kunye nokusilela kwi-folic acid edityanisiweUmthombo othembekileyo kukungasebenzi kakuhle kwe-erectile.
Izifundo ziye zafumanisa ukuba ukusela iikomityi ezimbini zekofu ngemini kunokuthintela ukungasebenzi kakuhle kwe-erectile. Oku kubulela esona sithako sithandwayo sekofu: icaffeine.
Ifunyenwe kwisosi eshushu kunye nepelepele, i-capsaicin ibangela ukukhutshwa kwee-endorphins- i "hormone elungileyo" - kwaye inokuhlaziya i-libido.

Q: Ngaba i-tadalafil iyayinyusa i-testosterone?

A; Unyango nge-PDE5I tadalafil yeeveki ezili-12 yayinxulumene nokwanda komlinganiso we testosterone / estradiol kunye nomsebenzi ophuculweyo wokukhuphela. I-Tadalafil ikwanakho nokunyusa amanqanaba e-serum ye-LH, ukunciphisa ii-cytokines ezinamandla, kunye nokunciphisa ubunzima besisu esiswini.

Umbuzo: Ngaba i-cialis ibhetele kune-tadalafil?

A: Izifundo zibonise ichiza i-tadalafil kunye negama lalo lorhwebo I-Cialis ukuba inqanaba lokuphumelela le-60-70% kunyango lwe-ED. I-Tadalafil (i-genial Cialis), iyasebenza ngokuchanekileyo.

Q: Ngaba umkhwa we-tadalafil uyila?

A: Akukho bungqina bobunzululwazi bokuba i-sildenafil, i-tadalafil okanye amanye amayeza asetyenziselwa ukunyanga ukungasebenzi kakuhle emzimbeni

Umbuzo: Ngaba ungayithatha i-tadalafil ngotywala?

A: Sukusela utywala kakhulu (umzekelo, iiglasi ezi-5 okanye ezingaphezulu zewayini okanye i-5 okanye ngaphezulu kwe-whisky) xa uthatha i-tadalafil. Xa uthathwe ngokugqithileyo, utywala bunokunyusa amathuba okufumana intloko okanye isiyezi, wandise izinga lokubetha kwentliziyo yakho, okanye wehlise uxinzelelo lwegazi.

Q: Ngaba i-Cialis mihla le iyonyusa i-testosterone?

A: I-5 mg tadalafil mihla le iphucule kakhulu i-ED ngenxa yokunyuka kwenqanaba le testosterone.

Q: Kwenzeka ntoni ukuba i-tadalafil ayisebenzi?

A; Ukuba i-tadalafil kunye nezinye i-PDE5 inhibitors azikusebenzeli, umboneleli wakho wezempilo unokucebisa ngezinye iindlela zonyango kubandakanya (AUA, 2018): Unyango lweTesttosterone: Uvavanyo lwegazi lubonisa amanqanaba asezantsi e-testosterone. Inaliti kwilungu lobudoda: Alprostadil kunye namanye amayeza.

Q: Kwenzeka ntoni ukuba uthatha i-tadalafil eninzi?

A: Ukuba uthatha i-tadalafil eninzi okanye uyithatha kunye nala mayeza, ithuba leziphumo ebezingalindelekanga liya kuba phezulu. Ukuba ufumana ulwakhiwo olude ngaphezulu kweeyure ezingama-4 okanye ulwaziso olubuhlungu ngaphezulu kweeyure ezingama-6, nxibelelana nogqirha ngokukhawuleza.

Q: Ngaba iTadalafil ikhuselekile?

A: Ngaba i-tadalafil iyeza elikhuselekileyo? Ngokubanzi, i-tadalafil sisiyobisi esikhuselekileyo kodwa ayikhuthazwa ukuba ithathwe ukuba uneemeko ezithile okanye uthatha amayeza athile anokusebenzisana ne-tadalafil.

Umbuzo: Ngaba Ijusi yamagilebhisi ilungile kwi-erectile dysfunction?

A: Ulwazi lweklinikhi aluphelelanga, kodwa amadoda athatha iViagra kufuneka aqonde ukuba ijusi yegrapefruit inokunyusa amanqanaba egazi leziyobisi. Oko kunokuba yinto elungileyo kwamanye amadoda ane-erectile dysfunction, kodwa inokubangela iintloko, ukugungxula, okanye uxinzelelo lwegazi.

Umbuzo: Ndingenza njani ukuba i-tadalafil isebenze ngcono?

A: 1. Gcina ubunzima obunempilo ngokunciphisa ubungakanani beesahlulo, ukutya ukutya okupheleleyo, kunye nokwenza ukhetho olusempilweni.
2. Yeka ukutshaya kunye nokusetyenziswa kwezinye iimveliso zecuba.
3.Yandisa umsebenzi womzimba ukunceda ukunciphisa uxinzelelo lwegazi kunye ne-cholesterol ephezulu.

Q: Ithatha ixesha elingakanani ukusebenza kwe-tadalafil?

A: Ihlala ithatha imizuzu engama-30 ukuya kwengama-60 kwi-tadalafil ukusebenzela ukungasebenzi kakuhle kwe-erectile. Ungayithatha kube kanye ngemini, ubuncinci imizuzu engama-30 ngaphambi kokuba ulale ngesondo.

Umbuzo: Ngaba kufuneka ndithathe iCialis kusasa okanye ebusuku?

A: Iitafile zeTadalafil ezandisiweyo zeprostate ziza njenge-2.5mg okanye i-5mg. Idosi eqhelekileyo yi-5mg, ithathwa kube kanye ngemini. Ungayithatha ithebhulethi yakho kusasa okanye ngokuhlwa, kodwa kungcono ukuyithatha ngexesha elifanayo yonke imihla. Ugqirha wakho unokukunika idosi esezantsi ye-2.5mg ukuba unengxaki, ezinje ngeziphumo ebezingalindelekanga.

Umbuzo: Ngaba ndingasela ikofu kunye neCialis?

A: Akukho ntsebenziswano ifunyenwe phakathi kwe-caffeine kunye neCialis.

Umbuzo: Ngaba iCialis inganciphisa iprostate?

A: Okt. I-6, 2011 -I-Cialis yamkelwe yi-FDA kunyango lweprostate eyandisiweyo. Ingasetyenziselwa ukunyanga amadoda anokwandiswa kweprostate kunye nokungasebenzi kakuhle kwe-erectile (ED) ngaxeshanye.

Umbuzo: Ngaba iTadalafil isebenza kwabasetyhini?

A: Eli yeza lisetyenziselwa ukunyanga ukungasebenzi kakuhle kwe-erectile kunye neempawu kunye neempawu ze-BPH. I-Tadalafil ikwasetyenziswa kumadoda nakwabafazi ukunyanga iimpawu ze-pulmonary arterial hypertension ukuphucula amandla akho omthambo.

Umbuzo: Uyithatha njani i-tadalafil yezona ziphumo zibalaseleyo?

A: I-Tadalafil (i-Cialis) iyafumaneka kwiinguqulelo ze-generic kunye ne-brand kwiidosi ezininzi njengecwecwe lomlomo. Ungathatha i-Cialis njengoko kufuneka okanye kube kanye ngosuku, kuxhomekeke kumthamo kunye nendlela emiselweyo ngayo. I-Cialis ithatha ukusuka kwimizuzu engama-30 ukuya kwiiyure ezi-2 ukuze iqale ukusebenza. Inokuhlala kwiiyure ezingama-36.

Umbuzo: Ngaba ndingathatha i-tadalafil 20 mg yonke imihla?

A: Idosi ephezulu yeCialis enokuthi ithathwe ngemini yi-20 mg. Akufanele uthathe iCialis ngaphezu kweyodwa ngosuku. Kwezilingo zeklinikhi, uCialis wanceda abantu abaneempawu ze-ED ukuya kuthi ga kwiiyure ezingama-36 emva kwedosi yabo. Ke ukuba uthatha amayeza kuphela njengoko kufuneka, akufuneki ukuba uwathathe yonke imihla

Q: Ndingathatha i-2 tadalafil 5mg?

A: I-Tadalafil (i-Cialis) iyafumaneka kwiinguqulelo ze-generic kunye ne-brand kwiidosi ezininzi njengecwecwe lomlomo. Ungathatha i-Cialis njengoko kufuneka okanye kube kanye ngosuku, kuxhomekeke kumthamo kunye nendlela emiselweyo ngayo. I-Cialis ithatha ukusuka kwimizuzu engama-30 ukuya kwiiyure ezi-2 ukuze iqale ukusebenza.

Q: Ngaba i-tadalafil inyusa uxinzelelo lwegazi?

A: Ukuncitshiswa koxinzelelo lwegazi kuwo wonke umzimba kunokwenzeka ngenxa yokuba i-tadalafil ibuyisa imithambo yegazi (imithambo) emzimbeni wonke. Isilumkiso kufuneka sisetyenziswe kwizigulana ezinexinzelelo lwegazi oluphantsi- umzekelo, ngaphantsi kwe-90/50 mmHg.

Q: Zithini iziphumo zecala le-tadalafil?

A: Intloko ebuhlungu, isisu esibuhlungu, iintlungu zomqolo, iintlungu zemisipha, impumlo exineneyo, ukugungxula, okanye isiyezi zinokwenzeka. Ukuba nayiphi na yezi ziphumo iqhubeka okanye iba mandundu, xelela ugqirha wakho okanye usokhemesti ngokukhawuleza. Ukunciphisa umngcipheko wokuba nesiyezi kunye nobunzima bentloko, sukuma kancinci xa unyuka kwindawo ohleli kuyo okanye olele kuyo.

Q; Ndingathatha i-tadalafil yonke imihla?

A: I-Tadalafil (i-Cialis) yenye yezona ziyobisi zidume ngokungasebenzi kakuhle (i-ED). Eyona nto yayinomtsalane kuye? Iyeza liza kwiinguqulelo zedosi ephantsi ezinokuthathwa yonke imihla.

Umbuzo: Ngaba i-tadalafil ilungile entliziyweni?

A: Ke oososayensi abaphuhlisa iViagra bafumanisa ukuba ichiza liyakhulula i-ED. "Sinobungqina obulinganiselweyo obuvela kwizilingo zabantu kunye nezifundo zesifo esibonisa ukuba iTadalafil inokusebenza ekunyangeni ukusilela kwentliziyo,"

Q: Ngaba i-tadalafil 5mg ikhuselekile?

A: Idosi yemihla ngemihla ye-5mg tadalafil inokusetyenziswa ngokukhuselekileyo kunyango lwe-erectile dysfunction kunye ne-LUTS, eyolula ixesha lokujikeleza kwe-ejaculatory.

Q: Ngaba i-tadalafil iyalunciphisa uxinzelelo lwegazi?

A: i-tadalafi inokuhlisa uxinzelelo lwegazi. Le asiyongxaki kuninzi lwamadoda, kodwa ifuthe le-tadalafi kuxinzelelo lwegazi libaxiwe ukuba i-tadalafi ithathwa ngesiyobisi se-nitrate. Iitrayitrate lolunye lonyango olumiselwe i-angina.

Q: Ngaba i-tadalafil ilungile kwi-Prostate eyandisiweyo?

A: I-Tadalafil (i-Cialis) kuphela kwesiyobisi esivunyiweyo yi-FDA ye-BPH, ekwabizwa ngokuba yi-Prostate eyandisiweyo. Ikwamiselwa ukuba unengxaki yokufumana okanye yokugcina ulwakhiwo.

Umbuzo: Ngaba iTadalafil ikwenza uhlale ixesha elide?

A: Ngawaphi amayeza ahlala ixesha elide? -I-Cialis (tadalafil). Nangona kunjalo, iViagra lelona nyango laziwa kakhulu ngokungasebenzi kakuhle emzimbeni, iCialis ineyona miphumo ihlala ixesha elide. I-Cialis ikwabandakanya ukucwangciswa okuncinci kodwa iziphumo ebezingalindelekanga zinokuhlala ixesha elide nazo.

Umbuzo: Ngaba ijusi yamagilebhisi iyenza i-Cialis yomelele?

A: Ukutya i-grapefruit okanye ukusela i-juice ye-grapefruit kunokunyusa amanqanaba e-tadalafil egazini lakho. Oku kuphakamisa umngcipheko weziphumo ebezingalindelekanga.

Q: Nguwuphi umahluko phakathi kweCialis kunye neTadalafil?

A: Uluhlu olude lweenkampani luye lwamkelwa yi-FDA ukuvelisa i-tadalafil yokunyanga i-ED kunye ne-BPH. Iinguqulelo eziqhelekileyo zeCialis ezivunyiweyo yi-FDA zisebenza ngokulinganayo kwaye zikhuselekile njengegama lophawu lweCialis. Iinguqulelo zesiqhelo zihlala zingaphantsi kwesiqingatha seendleko.

Umbuzo: Ngaba ndingayaphula iCialis ngesiqingatha?

Nokuba usempilweni kangakanani na, ngonyango kufuneka uvelise isidoda rhoqo kwiintsuku ezi-3 ukuya kwiveki enye ngeentsuku ezisi-1, ke ukubona ugqirha wakho kubaluleke kakhulu ukuyalela ngexesha ukuba kukho ukungahambi kakuhle.

Ucaphulo

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